Maternal Floor Infarction Placenta

Maternal floor infarction mfi is an uncommon placental disease associated with recurrent third trimester fetal loss and intrauterine growth retardation iugr usually severe. In maternal floor infarction mfi the floor of the placenta is thickened stiffened and often yellow. A placental infarction results from the interruption of blood supply to a part of the placenta causing its cells to die.

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Placental Pathology Placental Pathology Medical Education

Chronic Villitis Chronic Chorioamnionitis And Maternal Floor Infarction Pubmed Ncbi Science Journal Chronic Life Science

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Placental floor infarction as well as severe basal villitis are two additional causes of difficult placental separation lmc 03 2618 placenta previa.

Maternal floor infarction placenta. The disease is characterized by extensive fibrin deposition in the intervillous spaces. Maternal floor infarction frequently recurs in successive pregnancies rate 39 2 and there is evidence that it develops rapidly. Small placental infarcts especially at the edge of the placental disc are considered to be normal at term large placental infarcts are associated with vascular abnormalities e g. The pathophysiology of the lesion remains unclear.

Maternal floor infarction is associated with intrauterine growth retardation and fetal demise. Maternal floor infarction mfi is a poorly understood placental lesion reportedly associated with intrauterine growth restriction iugr and recurrence. Maternal floor infarction of the placenta is a relatively rare disorder that leads to sudden iufd 2 incidence. It is characterized by the deposition of fibrin in the decidua basalis and intervillous space where enveloped villi become avascular and sclerotic.

This website is intended for pathologists and laboratory personnel but not for patients. In this study of mfi and the related placental disorder massive perivillous fibrin deposition mfd semiquantitative histologic criteria for the. It is formally known as placental maternal floor infarction it is also known as massive perivillous fibrin deposition. Maternal floor infarction abbreviated mfi is a pathology of the placenta.

Maybe see some micro organization of exposed basal placental surface and admixed wbcs with elsewhere more normal. Hypertrophic decidual vasculopathy as seen in hypertension. Placenta maternal floor infarction. Very hard for pathologist to diagnose.

Massive perivillous fibrin deposition of the placenta mpfd or maternal floor infarction mfi is characterized by the extensive deposition of fibrinoid materials surrounding chorionic villi hampering gas and nutrient exchange in the intervillous space first described by benirschke and driscoll in 1967 this condition is associated with recurrent serious adverse pregnancy. Maternal floor infarction is not a true infarct. It frequently recurs in successive pregnancies. The maternal surface has a corrugated appearance and the placental septa are prominent figure 274.

Often the lesion is associated with excessive x cell proliferation and cyst formation figure 275.

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