Mat Test For Leptospira

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Mat test for leptospira. The mat tests for leptospira specific antibodies whereas the other tests demonstrate the presence of the organism itself. A single mat titer of 1 200 on any sera or identification of spirochetes on dark field microscopy when accompanied by the appropriate clinical scenario is strongly suggestive. Agglutination test mat has been the most common diagnostic method used for the diagnosis of canine leptospirosis 10 vaccination with commercially available leptospirosis vaccines will produce detectable mat titers 10 see algorithm 2 for more information on mat results. Leptospira are gram negative spirochetes with at least 20.
Leptospirosis is a zoonotic disease of worldwide prevalence though the majority of infections occur in warm tropical climates. Pcr on post mortem tissues such as liver or kidney and abortion tissues such as placenta fetal kidney or fetal stomach contents are. Testing may include culture and or serology. Bratislava canicola grippotyphosa hardjo icterohaemorrhagiae and pomona.
Microscopic agglutination test the mat is the gold standard when testing for leptospirosis. In addition to mat serology leptospira real time pcr testing on blood urine or ocular fluids may be of diagnostic value in highly suspect clinical cases especially when the duration of illness is not known. A severe form which includes jaundice kidney failure and bleeding is called weil disease. Additional leptospira testing options.
The microscopic agglutination test mat is the reference test for the diagnosis of leptospirosis. Our canine leptospiral mat test code 95055 includes antibody titers against the following six leptospiral serovars. The microscopic agglutination test mat is the basis of serological diagnosis and classification. The mixture is then examined under a dark field microscope to look for agglutination.
Human leptospirosis is an acute febrile illness that presents with many manifestations and is found worldwide. Read more did this. Titers against serovar autumnalis are available in our expanded panel test code 95066 or as an add on test code 95054 by request. Microscopic agglutination test mat for the diagnosis of leptospirosis and serotyping of leptospires h.
Wild mammals typically rodents are the primary natural reservoir for pathogenic strains of leptospira however domestic animals eg dogs also represent a major source of human infection. Leptospira panel 5 serovars mat detection of antibodies to 5 serovars of leptospira by quantitative microscopic agglutination test. Korver department of biomedical research royal tropical institute meibergdreef 39 11005 az amsterdam the netherlands get pdf file. 2 4 for this test the patient s serum is sent to a referral laboratory where it is combined with live leptospires.