Maternal Floor Infarction

There is no method to evaluate the risk of adverse outcome in subsequent pregnancies or effective prevention.

Maternal floor infarction. Essentially for some reason my immune system was able to recognize his placenta where normally it would be invisible. Massive perivillous fibrin deposition of the placenta mpfd or maternal floor infarction mfi is a serious condition associated with recurrent complications including fetal death and severe fetal growth restriction. The disease is characterized by extensive fibrin deposition in the intervillous spaces. Maternal floor infarction a pathologic entity characterised by deposition of fibrinoid material in the maternal surface and intervillous spaces of the placenta and which is associated with significant perinatal morbidity and mortality including stillbirth recurrent pregnancy loss premature delivery intrauterine growth restriction and neurodevelopmental impairment.

The enveloped villi become atrophic and avascular. Maternal floor infarction in an attempt to determine the frequency course and outcome of maternal floor infarcts 39 215 placentas and pregnancies were reviewed. It is also known as massive perivillous fibrin deposition. The disorder is somewhat misnamed because it is characterized by heavy deposition of fibrin in the decidua beneath the placenta rather than by arterial occlusion.

Maternal floor infarction mfi is an uncommon placental disease associated with recurrent third trimester fetal loss and intrauterine growth retardation iugr usually severe. Definition general massive deposition of intervillous fibrin that entrap the villi of the basal plate extending to a thickness of at least 3 mm may be accompanied by massive perivillous fibrin deposition associated with recurrent abortions stillbirth fetal growth restriction or neurologic impairment. Placental dysfunction appears late in the process of the disease and the lesion develops rapidly within hours. Maternal floor infarction maternal floor infarction abbreviated mfi is a pathology of the placenta.

Maternal floor infarction is a rare placental lesion of unknown etiology and is often associated with sudden intrauterine fetal demise and intrauterine growth restriction. As a refresher the issue in luke s pregnancy was a condition known variously as massive perivillous fibrin deposition maternal floor infarction chronic hystiocitic intervillositis and villitis of unknown etiology. It is formally known as placental maternal floor infarction.