Maternal Floor Infarction Pregnancy

The disease is characterized by extensive fibrin deposition in the intervillous spaces.

Maternal floor infarction pregnancy. Massive perivillous fibrin deposition mpvfd and maternal floor infarction mfi are pregnancy complications of unknown aetiology characterised by extensive deposition of fibrin either within the intervillous space or primarily within and around the basal plate. Maternal floor infarction mfi is an uncommon placental disease associated with recurrent third trimester fetal loss and intrauterine growth retardation iugr usually severe. Maternal floor infarction is not a true infarct. Maternal floor infarction a pathologic entity characterised by deposition of fibrinoid material in the maternal surface and intervillous spaces of the placenta and which is associated with significant perinatal morbidity and mortality including stillbirth recurrent pregnancy loss premature delivery intrauterine growth restriction and neurodevelopmental impairment.

Maternal floor infarction abbreviated mfi is a pathology of the placenta. The enveloped villi become atrophic and avascular. Up to 70 of fetuses born from a pregnancy complicated by mfi have neurological and or developmental impairment especially white matter infarction. The disorder is somewhat misnamed because it is characterized by heavy deposition of fibrin in the decidua beneath the placenta rather than by arterial occlusion.

It frequently recurs in successive pregnancies. In an attempt to determine the frequency course and outcome of maternal floor infarcts 39 215 placentas and pregnancies were reviewed. It is characterized by the deposition of fibrin in the decidua basalis and intervillous space where enveloped villi become avascular and sclerotic. Maternal floor infarction has important implications for the fetus that extend beyond the perinatal period.

As a refresher the issue in luke s pregnancy was a condition known variously as massive perivillous fibrin deposition maternal floor infarction chronic hystiocitic intervillositis and villitis of unknown etiology. It is formally known as placental maternal floor infarction it is also known as massive perivillous fibrin deposition. Maternal floor infarction frequently recurs in successive pregnancies rate 39 2 and there is evidence that it develops rapidly. Essentially for some reason my immune system was able to recognize his placenta where normally it would be invisible.