Maternal Floor Infarction Histology
Placental Pathology Placental Pathology Medical Education
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In an attempt to determine the frequency course and outcome of maternal floor infarcts 39 215 placentas and pregnancies were reviewed.
Maternal floor infarction histology. Klatt md department of pathology university of utah health sciences. Placenta maternal floor infarction. In this study of mfi and the related placental disorder massive perivillous fibrin deposition mfd semiquantitative histologic criteria for these diagnoses are defined and rates of iugr and. In maternal floor infarction mfi the floor of the placenta is thickened stiffened and often yellow.
Al sahan n 1 grynspan d von dadelszen p gruslin a. It has a very high recurrence rate and carries a significant risk or fetal demise. The recurrence rate varies from 14 to 39. The maternal surface has a corrugated appearance and the placental septa are prominent figure 274.
Often the lesion is associated with excessive x cell proliferation and cyst formation figure 275. 1 department of obs gyn division of maternal fetal medicine the ottawa hospital university of ottawa ottawa ontario canada. Vernof kk et al. Maternal floor infarction mfi is a poorly understood placental lesion reportedly associated with intrauterine growth restriction iugr and recurrence.
Maternal floor infarction mfi is a poorly understood placental lesion reportedly associated with intrauterine growth restriction iugr and recurrence. Maternal floor infarction has important implications for the fetus that extend beyond the perinatal period. Maternal floor infarction is a relatively rare condition characterized clinically by severe early onset fetal growth restriction with features of uteroplacental insufficiency. Relationship to x cells major basic protein and adverse perinatal outcome.
It is formally known as placental maternal floor infarction it is also known as massive perivillous fibrin deposition. The disorder is somewhat misnamed because it is characterized by heavy deposition of fibrin in the decidua beneath the placenta rather than by arterial occlusion. Contributed by ryan mccune md and edward c. This website is intended for pathologists and laboratory personnel but not for patients.
Maternal floor infarction abbreviated mfi is a pathology of the placenta. Management of an underrecognized pathology.
